Research just published online in the Journal of Biological Chemistry ¹ identifies a new molecule involved in the regulation of oestrogen receptors (ER) expression in breast cancer. Oestrogen is an hormone known to affect directly the survival and growth of breast cancer, and its activity is mediated through ER, which are, not only important prognostic factors in the disease, but also involved in the resistance to therapy observed in many of these tumours. The discovery, by elucidating part of the mechanism behind ER, can help to understand better breast cancer, and, in consequence, also the development of new and better therapies for the disease.

*  "This article is the result of a project for the divulgation of portuguese science" http://www.cienciahoje.pt/1455"